SAE2 Antibody Blocking Peptide

Product Discontinued

SAE2 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 18 amino acids near the carboxy terminus of human SAE2.

  Source: Synthetic

  (Accession #: NP_005490)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: UBA2
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-77162.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for SAE2 Antibody Blocking Peptide

• Anthracycline-associated resistance ARX
• ARX
• EC 6.3.2
• EC 6.3.2.-
• FLJ13058
• HRIHFB2115
• SAE2SUMO-1 activating enzyme subunit 2
• SUMO1 activating enzyme subunit 2
• SUMO-activating enzyme subunit 2
• UBA2, ubiquitin-activating enzyme E1 homolog
• Ubiquitin-like 1-activating enzyme E1B
• ubiquitin-like modifier activating enzyme 2
• UBLE1B

Background

Covalent attachment of one protein to another is one of the more prominent posttranslational modifications in respect to size and ubiquity. Ubiquitin is the most familiar of the protein modifiers and its activation and transfer to target proteins has been studied extensively. Recently, a new group of ubiquitin-like proteins has been receiving a lot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicated in the stabilization of target proteins and/or their localization to sub-cellular complexes. The conjugation of SUMO-1, SUMO-2 and SUMO-3 onto target proteins requires the concerted action of the specific E1-activating enzyme SAE1/SAE2, the E2-conjugating enzyme Ubc9, and an E3-like SUMO ligase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: UBA2