S100A6 Antibody (754102) [HRP]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 754102
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: HRP

S100A6 Antibody (754102) [HRP] Summary

• Immunogen: E. coli-derived recombinant human S100A6
  Met1-Gly90
  Accession # P06703
• Specificity: Detects human S100A6 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse S100A6 and no cross-reactivity with recombinant human (rh) S100A1, rhS100A4, or rhS100B is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: S100A6
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for S100A6 Antibody (754102) [HRP]

• 2A9
• CABP
• CACY
• CACY5B10
• calcyclin
• Growth factor-inducible protein 2A9
• MLN 4
• PRA
• PRAS100 calcium binding protein A6 (calcyclin)
• Prolactin receptor-associated protein
• protein S100-A6
• S100 calcium binding protein A6
• S100 calcium-binding protein A6 (calcyclin)
• S100 calcium-binding protein A6
• S100A6

Background

S100A6 is a member of the S100 family of proteins, and may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Recent studies have found that S100A6 is induced by tumour necrosis factor-alpha via a NF-kappaB-dependent mechanism, which serves a role in limiting tumour necrosis factor-alpha-induced apoptosis by regulating p53 phosphorylation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: S100A6