RIN1 Antibody (1D11) - Azide and BSA Free

Sandwich ELISA: RIN1 Antibody (1D11) [H00009610-M01] - Detection limit for recombinant GST tagged RIN1 is approximately 0.03ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: ELISA
• Clone: 1D11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

RIN1 Antibody (1D11) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse RIN1 Antibody (1D11) - Azide and BSA Free (H00009610-M01) is a monoclonal antibody validated for use in ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: RIN1 (AAH14417, 646 a.a. ~ 755 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. VPPEASIATLNQLCATKFRVTQPNTFGLFLYKEQGYHRLPPGALAHRLPTTGYLVYRRAEWPETQGAVTEEEGSGQSEARSRGEEQGCQGDGDAGVKASPRDIREQSETT
• Specificity: RIN1 - Ras and Rab interactor 1
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: RIN1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
• Application Notes: Antibody reactive against recombinant protein on ELISA. GST alone used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for RIN1 Antibody (1D11) - Azide and BSA Free

• Ras and Rab interactor 1
• ras inhibitor 1
• Ras inhibitor JC99
• ras inhibitor RIN1
• Ras interaction/interference protein 1

Background

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RIN1
• Entrez:
  • 9610(Human)
• OMIM:
  • 605965(Human)
• Uniprot:
  • AAH14417(Human)