RIMS3 Antibody - BSA Free

Images

 
Western Blot: RIMS3 Antibody [NBP1-76874] - Human brain tissue lysate with Rims3 antibody at 1 ug/mL in the (A) absence and (B) presence of blocking peptide.
Immunohistochemistry: RIMS3 Antibody [NBP1-76874] - Human brain tissue with RIMS3 antibody at 5 ug/mL.
Immunohistochemistry-Paraffin: RIMS3 Antibody [NBP1-76874] - Human brain tissue with Rims3 antibody at 2.5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

RIMS3 Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human Rim3. The immunogen is located within amino acids 60 - 110 of Rim3. Amino Acid Squence: LPQPEGATKKLRSNIRR
Specificity
This antibody is predicted to have no cross-reactivity to other Rim proteins.
Predicted Species
Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RIMS3
Purity
Peptide affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 5 ug/ml
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 1 ug/ml
Control Peptide
RIMS3 Peptide (NBP1-76874PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for RIMS3 Antibody - BSA Free

  • KIAA0137
  • KIAA0237
  • Nim3
  • NIM3Rab-3 interacting molecule 3
  • Rab-3-interacting molecule 3
  • regulating synaptic membrane exocytosis 3
  • regulating synaptic membrane exocytosis protein 3
  • RIM 3
  • RIM3 gamma
  • RIM3

Background

Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity. This antibody is predicted to have no cross-reactivity to other Rim proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RIMS3
Uniprot