Rev-erb A alpha/NR1D1 Antibody (A8740A) [Unconjugated]

• Reactivity: Hu
• Applications: WB, IP, ELISA
• Clone: A8740A
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Suitable Sample Type: 23005

Rev-erb A alpha/NR1D1 Antibody (A8740A) [Unconjugated] Summary

• Immunogen: Recombinant human Rev-Erb alpha /NR1D1
  aa 2-130
• Specificity: This antibody specifically recognizes human Rev-Erb alpha but does not recognize human Rev-Erb beta. Not yet tested in other species.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: NR1D1
• Purity Statement: Protein A or G purified from ascites

Applications/Dilutions

• Dilutions:
  • Western Blot
  • Immunoprecipitation
  • Direct ELISA

Packaging, Storage & Formulations

• Storage: This antibody is stable for greater than six months when held at -20° C in a manual defrost freezer or at -70° C. Upon thawing, the antibody can be stored at 2° - 8° C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
• Buffer: A liquid formulation in physiologic saline with 0.1% NaN₃.
• Preservative: 0.1% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rev-erb A alpha/NR1D1 Antibody (A8740A) [Unconjugated]

• Ear-1
• EAR1nuclear receptor subfamily 1 group D member 1
• HREV
• NR1D1
• nuclear receptor subfamily 1, group D, member 1
• Reverb A alpha
• Rev-erb A alpha
• Rev-ErbAalpha
• Rev-erbA-alpha
• THRA1
• THRAL
• THRALrev-erbA-alpha
• V-erbA-related protein 1

Background

Reverse orientation c-erbA-1 gene alpha (Rev-Erb alpha, ear1; NR1D1) is a member of the Orphan Nuclear Receptor family. Rev-Erb alpha is expressed in skeletal muscles, brown fat, liver, heart, brain, pituitary, kidney, testis, lung, and hypothalamus. Rev-Erb alpha has broad roles in cell proliferation and physiology. Rev-Erb alpha expression is regulated along a circadian rhythm.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NR1D1