RED1 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: RED1 Antibody [NBP3-11887] - Immunofluorescence staining of mouse anterior horns of spinal cord at 6 months, 15 months and 26 months of age. Antibody used at 1:100 dilution and visualized using donkey anti-sheep conjugated to Alexa 555 dye (red color). The blue color is a fluorescent nuclear probe, TOPRO3. (Image modified from original in citation 1).

• Reactivity: Rt
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Unconjugated
• Format: BSA Free

RED1 Antibody - BSA Free Summary

• Immunogen: Sheep were immunized with a GST fusion protein containing amino acid sequence 6-66 of rat RED1 (Uniprot: P51400)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: ADARB1
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:1000
• Application Notes: .

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.08% Sodium Azide
• Purity: Ammonium sulfate precipitation

Alternate Names for RED1 Antibody - BSA Free

• ADAR2a
• ADAR2ADAR2g
• ADAR2a-L1
• ADAR2a-L2
• ADAR2a-L3
• ADAR2b
• ADAR2c
• adenosine deaminase, RNA-specific, B1
• double-stranded RNA-specific editase 1
• DRABA2
• DRADA2hRED1
• EC 3.5
• human dsRNA adenosine deaminase DRADA2
• human dsRNA adenosine deaminase DRADA2b, EC 3.510adenosine deaminase, RNA-specific, B1 (homolog of rat RED1)
• RED1 homolog
• RED1ADAR2d
• RNA editase
• RNA editing deaminase 1
• RNA-editing deaminase 1
• RNA-editing enzyme 1
• RNA-specific, B1 (RED1 homolog rat)

Background

RED1 encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADARB1
• Uniprot:
  • P51400(Rat)