RECQL4 Antibody

Product Discontinued

RECQL4 Antibody Summary

• Immunogen: This antibody is specific for the N Terminus Region of the target protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RECQL4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:250-1:2000
  • Western Blot
• Application Notes: Use in WB reported in scientific literature (PMID:33674555).

Reactivity Notes

Use in Human reported in scientific literature (PMID:33674555).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Potassium Phosphate (pH 7.0), 0.15 M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for RECQL4 Antibody

• DNA helicase, RecQ-like type 4
• DNA helicase, RecQ-like, type 4
• EC 3.6.4.12
• RecQ protein-like 4RTS
• RecQ4
• RECQ4ATP-dependent DNA helicase Q4

Background

RECQL4 is a DNA-dependent ATPase. May modulate chromosome segregation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RECQL4 Antibody (25470002)(7)

Publications using 25470002

• Tan Q, Niu K, Zhu Y et al. RNF8 ubiquitinates RecQL4 and promotes its dissociation from DNA double strand breaks Oncogenesis 2021-03-05 [PMID: 33674555] (WB, Human)
• Zhu X, Chen H, Yang Y et al. Distinct prognosis of mRNA expression of the five RecQ DNA-helicase family members - RECQL, BLM, WRN, RECQL4, and RECQL5 - in patients with breast cancer Cancer Manag Res 2018-12-05 [PMID: 30584360] (IF/IHC, Human)
• Fang H, Niu K, Mo D et al. RecQL4-Aurora B kinase axis is essential for cellular proliferation, cell cycle progression, and mitotic integrity. Oncogenesis 2018-09-12 [PMID: 30206236] (WB, Human)
• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Mo D, Fang H, Niu K et al. Human helicase RECQL4 drives cisplatin resistance in gastric cancer by activating an AKT-YB1-MDR1 signaling pathway. Cancer Res. 2016-03-24 [PMID: 27013200] (WB, IHC-P, Human)
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.
• Kohzaki M, Chiourea M, Versini G, Adachi N, Takeda S, Gagos S, Halazonetis TD. The helicase domain and C-terminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiation. Carcinogenesis. 2012-04-26 [PMID: 22508716] (WB, Human)

Review for RECQL4 Antibody (25470002) (1)

Average Rating: 3

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Verified Customer ELISA Human 11/09/2018

Summary

• Application: ELISA
• Sample Tested: Serum and Plasma
• Species: Human
• Lot: T00417-A1

Bioinformatics

• Gene Symbol: RECQL4
• Entrez:
  • 9401(Human)
• Uniprot:
  • O94761(Human)