RECK Antibody [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 647

RECK Antibody [Alexa Fluor® 647] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human RECK
  Gly27-Val934
  Accession # O95980
• Specificity: Detects human RECK in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for RECK Antibody [Alexa Fluor® 647]

• hRECK
• membrane-anchored glycoprotein (metastasis and invasion)
• RECK
• reversion-inducing-cysteine-rich protein with kazal motifs
• ST15
• ST15reversion-inducing cysteine-rich protein with Kazal motifs
• suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein withkazal motifs)
• suppression of tumorigenicity 5 (reversion-inducing-cysteine-rich protein withkazal motifs)
• Suppressor of tumorigenicity 15 protein

Background

RECK is a GPI-anchored membrane protein that is highly expressed in most of the human tissues and untransformed cells, but is undetectable in tumor cells. RECK can negatively regulate MMP-9, MMP-2 and MTI-MMP activity and inhibit tumor angiogenesis and metastasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.