Recombinant Human RASL12 His Protein

SDS-Page: RASL12 Recombinant Protein [NBP2-51880] - 15% SDS Page (3 ug)

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.5 mg/ml

Recombinant Human RASL12 His Protein Summary

• Description: A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-266 of Human RASL12
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSSVFGK PRAGSGPQSA PLEVNLAILG RRGAGKSALT VKFLTKRFIS EYDPNLEDTY SSEETVDHQP VHLRVMDTAD LDTPRNCERY LNWAHAFLVV YSVDSRQSFD SSSSYLELLA LHAKETQRSI PALLLGNKLD MAQYRQVTKA EGVALAGRFG CLFFEVSACL DFEHVQHVFH EAVREARREL EKSPLTRPLF ISEERALPHQ APLTARHGLA SCTFNTLSTI NLKEMPTVAQ AKLVTVKSSR AQSKRKAPTL TLLKGFKIF

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: RASL12
• Purity: >85%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Application Notes: Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.
• Theoretical MW: 32.1 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH8.0), 10% glycerol
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >85%, by SDS-PAGE

Alternate Names for Recombinant Human RASL12 His Protein

• Ras family member Ris
• ras-like protein family member 12
• RAS-like, family 12
• RISRas-like protein Ris

Background

Belonging to the small GTPase superfamily/Ras family, RASL12 is localized in the cellular membrane and cytoplasm. RASL12 has many important molecular functions including GTP binding, GTPase activity and nucleotide binding. The main biological function of this gene is to participate in the GTP catabolic process, signal transduction and small GTPase mediated signal transduction. RASL12 interacts with ACVR1, SMAD1, SMAD2, SMAD3 and SMURF2. Documented diseases associated with RASL12 include acute kidney tubular necrosis, intraepithelial neoplasm, retinitis, endometrial cancer, coronary artery disease and Huntington's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: RASL12