Rad50 Antibody

Product Discontinued

Rad50 Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residues 700 and 750 of human Rad50 using the numbering given in entry NP_005723.2 (GeneID 10111).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RAD50
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:500-1:2000
  • Western Blot 1:1000-1:5000
• Application Notes: Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Rad50 Antibody

• DNA repair protein RAD50
• EC 3.6
• EC 3.6.1.15
• EC 3.6.3
• EC 3.6.3.27
• hRad50
• NBSLD
• RAD50 (S. cerevisiae) homolog
• RAD50 homolog (S. cerevisiae)
• Rad50
• RAD502
• RAD50-2

Background

Rad50, a 153kDa protein involved in DNA double strand break repair, is associated with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, Rad50 and Mre11 redistribute and are co-localized within the nucleus of damaged cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RAD50
• Entrez:
  • 10111(Human)
• Uniprot:
  • NP_005723.2(Human)