Western Blot: RAD18 Antibody [NB100-61063] - Detection of Human RAD18 on HeLa whole cell lysate using NB100-61063. RAD18 was also immunoprecipitated by rabbit anti-RAD18 antibody NB100-61062.
Proximity Ligation Assay: RAD18 Antibody [NB100-61063] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human ATM (NB100-271) and rabbit anti-human RAD18 (NB100-61063). Image merged from DAPI (2ms) and ...read more
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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