RAC2 Antibody (2G11)

Product Discontinued

RAC2 Antibody (2G11) Summary

• Immunogen: Recombinant human RAC2 (1-189aa) protein purified from E. coli
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: RAC2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 10% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for RAC2 Antibody (2G11)

• Gx
• HSPC022
• ras-related C3 botulinum toxin substrate 2 (rho family, small GTP bindingprotein Rac2)
• rho family, small GTP binding protein Rac2
• small GTP-bindingprotein Rac2)

Background

Rac2(Ras-related C3 botulinum toxin substrate 2), a small (21 kDa) signaling G protein, belongs to the family of Rho GTPases regulating a variety of biological response pathways that include cell motility, cell division, gene transcription, and cell transformation. Upon GTP loading, a conformational change takes place that allows Rac2 protein to interact with several downstream effectors that ultimately process the information and propagate the signal within the cell, causing changes in the actin cytoskeleton, release of inflammatory modulators and innate immunity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RAC2
• Uniprot:
  • NP_ 002863(Human)