RAC2 Products

Antibodies
RAC2 Antibody (3B8)
RAC2 Antibody (3B8)
H00005880-M08
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
RAC2 Antibody
RAC2 Antibody
NBP1-33449
Species: Hu, Mu, Bovine, Monkey
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
RAC2 Antibody
RAC2 Antibody
NBP2-31086
Species: Hu
Applications: WB, IHC, IHC-P
Host: Goat Polyclonal
Lysates
RAC2 Overexpression Lysate (N ...
RAC2 Overexpression Lysate (Native)
NBP2-08063
Applications: WB
Proteins
RAC2 Recombinant Protein
RAC2 Recombinant Protein
NBC1-18403
Species: Hu
Applications: PAGE
RAC2 Recombinant Protein
RAC2 Recombinant Protein
NBP1-30199
Species: Hu
Applications: PAGE
RNAi
RAC2 RNAi
RAC2 RNAi
H00005880-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

RAC2 is a plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, RAC2 binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. There are two isoforms of RAC2; isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins. It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish effector interaction.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 5880
Alternate Names
  • GX
  • HSPC022
  • rho family, small GTP binding protein Rac2
  • Gx
  • small GTP-bindingprotein Rac2)
  • ras-related C3 botulinum toxin substrate 2 (rho family, small GTP bindingprotein Rac2)

Research Areas for RAC2

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction
Wnt Signaling Pathway

Bioinformatics Tool for RAC2

Discover related pathways, diseases and genes to RAC2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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