Rabex5 Antibody - BSA Free

Western Blot: Rabex5 Antibody [NBP1-76548] - Analysis in human liver tissue lysate with antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry: Rabex5 Antibody - BSA Free [NBP1-76548] - Immunohistochemistry of Rabex5 in mouse brain tissue with Rabex5 antibody at 5 ug/mL.

Immunocytochemistry/ Immunofluorescence: Rabex5 Antibody - BSA Free [NBP1-76548] - Immunofluorescence of Rabex5 in mouse brain tissue with Rabex5 antibody at 20 ug/mL.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Rabex5 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Rabex5 Antibody - BSA Free (NBP1-76548) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 19 amino acid synthetic peptide near the center terminus of human RABEX5. The immunogen is located within amino acids 430 - 480 of RABEX5. Amino Acid Squence: PETTDDEKKDLAIQKRIRA
• Specificity: At least four isoforms of RABEX5 are known to exist; this antibody will recognize all four. RABEX5 antibody is predicted to not cross-react with other LRRFIP family members.
• Predicted Species: Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RABGEF1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1 ug/ml
• Control Peptide:

  Rabex5 Peptide (NBP1-76548PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for Rabex5 Antibody - BSA Free

• FLJ32302
• RAB guanine nucleotide exchange factor (GEF) 1
• rab5 GDP/GTP exchange factor
• Rabaptin-5-associated exchange factor for Rab5
• Rabex-5
• RABEX5rabex-5
• RAP1

Background

RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic. RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RABGEF1
• Uniprot:
  • NP_055319(Human)