PYGL Antibody

Immunohistochemistry-Paraffin: PYGL Antibody [NB100-58761] - Analysis of anti-PYGL antibody with human liver at concentration 10 ug/ml.

Product Discontinued

PYGL Antibody Summary

• Immunogen: Synthetic 10 amino acid peptide from internal region of human PYGL.
• Specificity: Human PYGL. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Primate (90%), Monkey (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PYGL
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (90%), Marmoset (90%), Mouse (80%), Sheep (80%), Hamster (80%), Equine (80%), Rabbit (80%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PYGL Antibody

• EC 2.4.1.1
• glycogen phosphorylase, liver form
• GSD6
• phosphorylase, glycogen, liver
• phosphorylase, glycogen; liver
• PYGL

Background

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. Activity of phosphorylase is controlled both by allosteric means (through the noncovalent binding of metabolites) and by covalent modification. Thus AMP allosterically activates, whereas ATP, ADP, and glucose 6 phosphate allosterically inhibit, phosphorylase B.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PYGL
• Entrez:
  • 5836(Human)
• Uniprot:
  • P06737(Human)