PTPN4 Antibody

Images

 
Western Blot: PTPN4 Antibody [NBP1-80867] - Analysis in human cell line HDLM-2.
Immunocytochemistry/ Immunofluorescence: PTPN4 Antibody [NBP1-80867] - Staining of human cell line U-2 OS shows localization to nucleus & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: PTPN4 Antibody [NBP1-80867] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: PTPN4 Antibody [NBP1-80867] - Staining of human duodenum shows moderate positivity in apical membrane in glandular cells.
Immunohistochemistry-Paraffin: PTPN4 Antibody [NBP1-80867] - Staining of human kidney shows strong membranous positivity in cells in tubules.

Product Details

Summary
Product Discontinued
View other related PTPN4 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-80867
    • Availability
      Product Discontinued

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PTPN4 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: EQGSSMVVMLTTQVERGRVKCHQYWPEPTGSSSYGCYQVTCHSEEGNTAYIFRKMTLFNQEKNESRPLTQIQYIAWPDHGVPDDSSDFL
Predicted Species
Mouse (94%), Rat (96%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PTPN4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
  • Western Blot 0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Publications
Read Publications using NBP1-80867.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PTPN4 Antibody

  • EC 3.1.3.48
  • MEG
  • megakaryocyte phosphatase
  • megakaryocyte protein-tyrosine phosphatase
  • protein tyrosine phosphatase MEG1
  • protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
  • Protein-tyrosine phosphatase MEG1
  • PTPase-MEG1
  • PTPMEG
  • PTPMEG1
  • PTPN4
  • tyrosine-protein phosphatase non-receptor type 4

Background

PTPN4 is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PTPN4 Antibody (NBP1-80867)(2)

We have publications tested in 2 confirmed species: Human, Mouse.


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Human
(1)
Mouse
(1)
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Showing Publications 1 - 2 of 2.
Publications using NBP1-80867 Applications Species
Zhang X, Lao M, Yang H et al. Targeting cancer-associated fibroblast autophagy renders pancreatic cancer eradicable with immunochemotherapy by inhibiting adaptive immune resistance Research Square 2022-11-09 (Mouse, Human) Mouse, Human
Cao Z, Liu J, Zhao Z, Wang Q miR-16-5p Regulates PTPN4 and Affects Cardiomyocyte Apoptosis and Autophagy Induced by Hypoxia/Reoxygenation Evidence-based complementary and alternative medicine : eCAM 2021-06-16 [PMID: 34306144]

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for PTPN4 Antibody (NBP1-80867) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for PTPN4 Antibody (NBP1-80867)

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Bioinformatics

Gene Symbol PTPN4
Entrez
Uniprot