PTP beta/zeta/PTPRZ Antibody - Azide and BSA Free

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free

Order Details

PTP beta/zeta/PTPRZ Antibody - Azide and BSA Free Summary

Description
Novus Biologicals Rabbit PTP beta/zeta/PTPRZ Antibody - Azide and BSA Free (NBP3-03169) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human PTP beta/zeta/PTPRZ (NP_001193767.1). VESVSRFGKQAALDPFILLNLLPNSTDKYYIYNGSLTSPPCTDTVDWIVFKDTVSISESQLAVFCEVLTMQQSGYVMLMDYLQNNFREQQYKFSRQVFSSY
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PTPRZ1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol
Preservative
0.01% Thimerosal
Purity
Affinity purified

Alternate Names for PTP beta/zeta/PTPRZ Antibody - Azide and BSA Free

  • 3F8 CSPG
  • HPTPZ
  • phosphacan
  • protein tyrosine phosphatase, receptor-type, Z polypeptide 1
  • PTP beta/zeta
  • PTP18
  • PTPRZ
  • PTPRZ1
  • PTPZ
  • receptor-type, zeta polypeptide 1
  • RPTPB
  • RPTPbeta

Background

PTPRB is a member of the protein tyrosine phosphatase (PTP) family. The family comprises at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. PTP1B is a transmembrane PTP. The PTPs have high substrate specificity for phosphotyrosyl proteins, at the primary sequence level sharing little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. PTP beta interacts with and regulates the tyrosine phosphorylation level of catenins, which are critical in physiological and pathological events such as cell migration, adhesion and transformation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

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Bioinformatics

Gene Symbol PTPRZ1