PTP beta/zeta/PTPRZ Products

Description

PTPRB is a member of the protein tyrosine phosphatase (PTP) family. The family comprises at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. PTP1B is a transmembrane PTP. The PTPs have high substrate specificity for phosphotyrosyl proteins, at the primary sequence level sharing little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. PTP beta interacts with and regulates the tyrosine phosphorylation level of catenins, which are critical in physiological and pathological events such as cell migration, adhesion and transformation.

Bioinformatics

Entrez	5803 Human
Uniprot	O76043 Human P23471 Human
Product By Gene ID	5803
Alternate Names	3F8 CSPG phosphacan protein tyrosine phosphatase, receptor-type, Z polypeptide 1 PTPZ receptor-type, zeta polypeptide 1 RPTPbeta

Research Areas for PTP beta/zeta/PTPRZ

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Stem Cell Markers