PTH Antibody (PTH/1175) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
PTH/1175
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

PTH Antibody (PTH/1175) [Janelia Fluor® 549] Summary

Immunogen
Recombinant fragment (84 amino acid residues from C-terminus) of human PTH protein
Localization
Cytoplasmic and Secreted
Specificity
Epitope of this MAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PTH
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for PTH Antibody (PTH/1175) [Janelia Fluor® 549]

  • Parathormone
  • Parathyrin
  • parathyroid hormone 1
  • parathyroid hormone
  • PTH
  • PTH1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47730AF350
Alexa Fluor 405 NBP2-47730AF405
Alexa Fluor 488 NBP2-47730AF488
Alexa Fluor 532 NBP2-47730AF532
Alexa Fluor 594 NBP2-47730AF594
Alexa Fluor 647 NBP2-47730AF647
Alexa Fluor 700 NBP2-47730AF700
Alexa Fluor 750 NBP2-47730AF750
Allophycocyanin NBP2-47730APC
Allophycocyanin/Cy7 NBP2-47730APCCY7
Biotin NBP2-47730B
DyLight 350 NBP2-47730UV
DyLight 405 NBP2-47730V
DyLight 488 NBP2-47730G
DyLight 550 NBP2-47730R
DyLight 594 NBP2-47730DL594
DyLight 650 NBP2-47730C
DyLight 680 NBP2-47730FR
DyLight 755 NBP2-47730IR
FITC NBP2-47730F
HRP NBP2-47730H
Janelia Fluor 549 NBP2-47730JF549
Janelia Fluor 646 NBP2-47730JF646
PE NBP2-47730PE
PE/Atto594 NBP2-47730PEATT594
PE/Cy5.5 NBP2-47730PECY55
PE/Cy7 NBP2-47730PECY7
PerCP NBP2-47730PCP

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Bioinformatics Tool for PTH Antibody (NBP2-47730JF549)

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Bioinformatics

Gene Symbol PTH
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