PSGL-1/CD162 Antibody (TC2)

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Flow (Cell Surface): PSGL-1/CD162 Antibody (TC2) [NBP1-44599] - Analysis using the PE conjugate of NBP1-44599. Surface staining of human peripheral blood cells with anti-human CD162 (clone TC2).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, Flow-CS, CyTOF-ready
Clone
TC2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

PSGL-1/CD162 Antibody (TC2) Summary

Immunogen
Human thymocytes.
Specificity
The antibody TC2 reacts with CD162, a 220 kDa type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family). CD162 is present on the most peripheral blood T lymphocytes, monocytes, granulocytes; it is also expressed on a subpopulation of B lymphocytes and CD34^+ bone marrow cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SELPLG
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1.5 - 2.5 ug/ml
  • CyTOF-ready
  • Flow (Cell Surface)
Publications
Read Publication using NBP1-44599.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
15mM Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for PSGL-1/CD162 Antibody (TC2)

  • CD162 antigen
  • CD162
  • P-selectin glycoprotein ligand 1
  • PSGL1
  • PSGL-1
  • PSGL-1cutaneous lymphocyte-associated associated antigen
  • selectin P ligandCLA
  • SELPLG

Background

CD162 (P-selectin glycoprotein ligand-1, PSGL-1) is a sialomucin constitutively expressed as a disulfide-linked homodimer of two 120 kDa subunits on the surface of circulating leukocytes. CD162 serves as a ligand for P- E- and L-selectin, with the highest affinity for P-selectin. It is thus involved in leukocyte rolling at the endothelial surfaces, prerequisite for firm leukocyte adhesion and subsequent transendothelial migration. CD162 also mediates leukocyte-platelet adhesion and interleukocyte contacts. Whereas serving as an adhession molecule on mature leukocytes, CD162 is a potent negative regulator of human hematopoietic progenitors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PSGL-1/CD162 Antibody (NBP1-44599)(1)

We have publications tested in 1 confirmed species: Human.


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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SELPLG
Entrez