PSGL-1/CD162 Products

Description

CD162, also known as p-selectin glycoprotein ligand-1 (PSGL-1), is a 120 - 220 kDa, mucin-like type I transmembrane glycoprotein. CD162 binds to CD62P (P-Selectin), CD62E (E-Selectin) and CD62L (L-Selectin). The interactions between P-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) mediate the earliest "rolling" of leukocytes on the lumenal surface of activated endothelium, and the interaction between leukocytes and activated platelets or other leukocytes found at sites of inflammation. CD162 is expressed on neutrophils, monocytes, and most lymphocytes including NK and T cells but PSGL-1 stains B cells at significantly lower levels than other cell types.

Bioinformatics

Entrez	20778 Mouse 6404 Human 949 Human
Uniprot	NP_002997 Human Q14242 Human
Product By Gene ID	6404
Alternate Names	CD162 antigen CD162 P-selectin glycoprotein ligand 1 PSGL1 PSGL-1cutaneous lymphocyte-associated associated antigen selectin P ligandCLA

Research Areas for PSGL-1/CD162

Find related products by research area and learn more about each of the different research areas below.

CD Markers
Cholesterol Metabolism
Immunology
Lipid and Metabolism