Proteasome subunit beta type 4 Antibody (OTI2C9)

Images

 
Western Blot: Proteasome subunit beta type 4 Antibody (2C9) [NBP2-01225] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Proteasome subunit beta type 4 (Right lane) cDNA for 48 ...read more
Immunohistochemistry-Paraffin: Proteasome subunit beta type 4 Antibody (2C9) [NBP2-01225] Staining of paraffin-embedded Human prostate tissue using anti-Proteasome subunit beta type 4 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Proteasome subunit beta type 4 Antibody (2C9) [NBP2-01225] - Staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-Proteasome subunit beta type 4 mouse monoclonal ...read more
Immunohistochemistry-Paraffin: Proteasome subunit beta type 4 Antibody (2C9) [NBP2-01225] - Staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-Proteasome subunit beta type 4 mouse ...read more
Immunohistochemistry-Paraffin: Proteasome subunit beta type 4 Antibody (2C9) [NBP2-01225] - Staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-Proteasome subunit beta type 4 mouse monoclonal ...read more
Immunohistochemistry-Paraffin: Proteasome subunit beta type 4 Antibody (2C9) [NBP2-01225] - Staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-Proteasome subunit beta type 4 mouse monoclonal ...read more
Immunohistochemistry-Paraffin: Proteasome subunit beta type 4 Antibody (2C9) [NBP2-01225] - Staining of paraffin-embedded Carcinoma of Human liver tissue using anti-Proteasome subunit beta type 4 mouse monoclonal ...read more
Immunohistochemistry-Paraffin: Proteasome subunit beta type 4 Antibody (2C9) [NBP2-01225] - Staining of paraffin-embedded Carcinoma of Human lung tissue using anti-Proteasome subunit beta type 4 mouse monoclonal ...read more
Immunohistochemistry-Paraffin: Proteasome subunit beta type 4 Antibody (2C9) [NBP2-01225] - Staining of paraffin-embedded Human endometrium tissue using anti-Proteasome subunit beta type 4 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Proteasome subunit beta type 4 Antibody (2C9) [NBP2-01225] - Staining of paraffin-embedded Human Kidney tissue using anti-Proteasome subunit beta type 4 mouse monoclonal antibody.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IHC-P
Clone
OTI2C9
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.59 mg/ml

Proteasome subunit beta type 4 Antibody (OTI2C9) Summary

Immunogen
Full length human recombinant protein of human PSMB4(NP_002787) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PSMB4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin 1:150
  • Western Blot 1:2000
Theoretical MW
29 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
0.59 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Proteasome subunit beta type 4 Antibody (OTI2C9)

  • EC 3.4.25.1
  • HN3
  • HsBPROS26
  • HsN3
  • Macropain beta chain
  • Multicatalytic endopeptidase complex beta chain
  • PROS26
  • PROS-26
  • PROS26PROS-26
  • proteasome (prosome, macropain) subunit, beta type, 4
  • Proteasome beta chain
  • Proteasome chain 3
  • Proteasome subunit beta type 4
  • proteasome subunit beta type-4
  • proteasome subunit HsN3
  • proteasome subunit, beta type, 4,26 kDa prosomal protein
  • PSMB4

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PSMB4
Entrez