Proteasome 20S alpha 6 Antibody (OTI4C9) [Allophycocyanin/Cy7]

Product Discontinued

Proteasome 20S alpha 6 Antibody (OTI4C9) [Allophycocyanin/Cy7] Summary

• Immunogen: Full length recombinant protein of human Proteasome 20S alpha 6 (NP_002782) produced in E.coli.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: PSMA6
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Cy is a registered trademark of Global Life Sciences Solutions Germany GmbH.

Alternate Names for Proteasome 20S alpha 6 Antibody (OTI4C9) [Allophycocyanin/Cy7]

• EC 3.4.25.1
• IOTA
• Macropain iota chain
• macropain subunit iota
• MGC22756
• MGC2333
• MGC23846
• Multicatalytic endopeptidase complex iota chain
• p27K
• p27KPROS-27
• PROS27
• PROS-27
• PROS2727 kDa prosomal protein
• prosomal P27K protein
• proteasome (prosome, macropain) subunit, alpha type, 6
• Proteasome 20S alpha 6
• Proteasome iota chain
• proteasome subunit alpha type-6
• proteasome subunit iota
• PSMA6

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PSMA6