Proliferin Antibody

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

Proliferin Antibody Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Proliferin
  Phe30-Cys224
  Accession # P04095
• Specificity: Detects mouse Proliferin in direct ELISAs and Western blots.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: Prl2c2
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Proliferin Antibody

• Ghd2;MRP-1;Plf;Plf1;PLF-1;Prl2c2;Prolactin-2C2
• MRP
• Proliferin

Background

Proliferin belongs to the large mouse somatotropin/prolactin family of peptide hormones. In mice, the proliferins are expressed during development and are also found in the adult placenta, skin, hair follicles and small intestines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Proliferin Antibody (AF1623)(7)

Publications using AF1623

• Vijay Pratap Singh, Huzaifa Hassan, Fengyan Deng, Dai Tsuchiya, Sean McKinney, Kevin Ferro et al. c-Myc promotes polyploidy in murine trophoblast cells and suppresses senescence Development 2023-06-01 [PMID: 37158673] (Immunocytochemistry, Human)
• Vijay Pratap Singh, Huzaifa Hassan, Fengyan Deng, Dai Tsuchiya, Sean McKinney, Kevin Ferro et al. c-Myc promotes polyploidy in murine trophoblast cells and suppresses senescence Development 6/1/2023 [PMID: 37158673]
• Hiroshi YOMOGITA, Hikaru ITO, Kento HASHIMOTO, Akihiko KUDO, Toshiaki FUKUSHIMA, Tsutomu ENDO et al. A possible function of <i>Nik-related kinase</i> in the labyrinth layer of delayed delivery mouse placentas Journal of Reproduction and Development 2/8/2023 [PMID: 36567126]
• Trishita Basak, Madhurima Paul, Rupasri Ain Protocol for functional characterization of endoreduplicated murine trophoblast cells STAR Protocols 9/1/2022 [PMID: 35880131]
• Sarbani Saha, Rupasri Ain MicroRNA regulation of murine trophoblast stem cell self-renewal and differentiation Life Science Alliance 11/1/2020 [PMID: 32907860]
• L Hu, Z Huang, H Ishii, H Wu, S Suzuki, A Inoue, W Kim, H Jiang, X Li, E Zhu, L Piao, G Zhao, Y Lei, K Okumura, GP Shi, T Murohara, M Kuzuya, XW Cheng PLF-1 (Proliferin-1) Modulates Smooth Muscle Cell Proliferation and Development of Experimental Intimal Hyperplasia J Am Heart Assoc, 2019-12-16;8(24):e005886. 2019-12-16 [PMID: 31838975] (IHC-Fr, Mouse, Rat)
• KYB Lamm, ML Johnson, J Baker Phil, MB Muntiferin, JM James, HN Jones, RW Redline, A Rokas, LJ Muglia Inverted formin 2 regulates intracellular trafficking, placentation, and pregnancy outcome Elife, 2018-01-08;7(0):. 2018-01-08 [PMID: 29309034] (IHC, Mouse)

Bioinformatics

• Gene Symbol: Prl2c2
• Uniprot:
  • P04095()