Profilin 1 Antibody (816536) [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: WB
• Clone: 816536
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

Profilin 1 Antibody (816536) [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant human Profilin 1
  Met1-Tyr140
  Accession # P07737
• Specificity: Detects human Profilin 1 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant human Profilin 2 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Profilin 1 Antibody (816536) [Alexa Fluor® 405]

• PFN1
• PROF1
• Profilin 1
• Profilin I
• profilin-1

Background

Profilin 1 (gene name PFN1) is a ubiquitous, cytoplasmic, 140 amino acid, 12-15 kDa actin monomer-binding protein. It facilitates adenine nucleotide exchange, supplying ATP for actin filament polymerization. It is phosphorylated and acetylated, and binds proline-rich sequences. Human Profilin 1 shares 96% amino acid sequence identity with mouse and rat Profilin 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.