Pregnancy Zone Protein Antibody (909855R) [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: ELISA
• Clone: 909855R
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

Pregnancy Zone Protein Antibody (909855R) [Alexa Fluor® 350] Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Human embryonic kidney cell line HEK293-derived recombinant human Pregnancy Zone Protein/ PZP
  Thr26-Val1482
  Accession # P20742
• Specificity: Detects human Pregnancy Zone Protein/PZP in direct ELISAs.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Pregnancy Zone Protein Antibody (909855R) [Alexa Fluor® 350]

• C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6
• CPAMD6
• Pregnancy Zone Protein
• pregnancy-zone protein
• PZP

Background

Pregnancy Zone Protein (PZP), also known as C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6, is a 360 kDa secreted homodimeric glycoprotein, PZP monomer contains a region of decisive functional importance i.e. the bait region. This region serves as a substrate to a variety of proteinases, and cleavage in this domain causes a conformational change of the molecule. Human PZP is a member of the protease inhibitor I39 (alpha-2-macroglobulin) family of proteins.  Highest expression of human PZP is reported in liver, medium expression in ovary, heart and stomach. Also, this protein is found in plasma.  Over amino acids (aa) 26-1482, human PZP shares 56% aa sequence identity with mouse PZP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.