PRDC/GREM2 Antibody - Azide and BSA Free

Western Blot: PRDC/GREM2 Antibody [H00064388-B01P] - Analysis of GREM2 expression in transfected 293T cell line by GREM2 polyclonal antibody. Lane 1: GREM2 transfected lysate(18.48 KDa). Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

PRDC/GREM2 Antibody - Azide and BSA Free Summary

• Immunogen: GREM2 (AAH46632.1, 1 a.a. - 168 a.a.) full-length human protein. MFWKLSLSLFMVAVLVKVAEARKNRPAGAIHSPYKDGSSNNSERWQHQIKEVLASSQEALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCYGQCNSFYIPRHVKKEEESFQSCAFCKPQRVTSVLVELECPGLDPPFRLKKIQKVKQCRCMSVNLSDSDKQ
• Specificity: GREM2 - gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: GREM2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Application Notes: Antibody reactive against transfected lysate for western blot. It has also been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PRDC/GREM2 Antibody - Azide and BSA Free

• CKTSF1B2
• CKTSF1B2FLJ21195
• Cysteine knot superfamily 1, BMP antagonist 2
• DAN domain family member 3
• DAND3
• DAND3Prdc
• GREM2
• gremlin 2
• gremlin 2, cysteine knot superfamily, homolog
• gremlin-2
• PRDC
• PRDCgremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)
• Protein related to DAN and cerberus

Background

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PRDC/GREM2 Antibody (H00064388-B01P)(1)

Publication using H00064388-B01P

• Wang J, Zheng L, Hu C et al. CircZFR promotes pancreatic cancer progression through a novel circRNA-miRNA-mRNA pathway and stabilizing epithelial-mesenchymal transition protein Cellular signalling 2023-03-27 [PMID: 36990335] (Western Blot, Human)

Bioinformatics

• Gene Symbol: GREM2
• Entrez:
  • 64388(Human)
• Uniprot:
  • AAH46632.1(Human)