PRDC/GREM2 Products

Description

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq]

Bioinformatics

Entrez	64388 Human
Uniprot	AAH46632 Human
Product By Gene ID	64388
Alternate Names	CKTSF1B2 CKTSF1B2FLJ21195 Cysteine knot superfamily 1, BMP antagonist 2 DAN domain family member 3 DAND3 DAND3Prdc GREM2 gremlin 2 gremlin 2, cysteine knot superfamily, homolog gremlin-2 PRDC PRDCgremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) Protein related to DAN and cerberus

Research Areas for PRDC/GREM2

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Stem Cell Markers