PRDC/GREM2 Products

Description

GREM2, also known as Gremlin-2, is a 168 amino acid that is 19 kDa, belongs to the DAN family, plays a role in the inhibition of the activity of BMP2 and BMP4 in a dose-dependent manner, and as an antagonist of BMP, it may play a role in regulating organogenesis, body patterning, and tissue differentiation. Current research is being performed on several diseases and disorders including astigmatism, myopia, accommodative esotropia, keratoconus, intraocular retinoblastoma, scimitar syndrome, swine influenza, influenza, norrie disease, and multiple sclerosis. The GREM2 protein is known to have an interaction with BMP4, BMP2, CER1, NOG, and FSTL1 in signal transduction and signaling by BMP pathways.

Bioinformatics

Entrez	64388 Human
Uniprot	AAH46632 Human AAH46632.1 Human NM_022469 Human Q9H772 Human
Product By Gene ID	64388
Alternate Names	CKTSF1B2FLJ21195 Cysteine knot superfamily 1, BMP antagonist 2 DAN domain family member 3 DAND3Prdc gremlin 2 gremlin 2, cysteine knot superfamily, homolog gremlin-2 PRDCgremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) Protein related to DAN and cerberus

Research Areas for PRDC/GREM2

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Stem Cell Markers