PPP4R2 Antibody - BSA Free

Western Blot: PPP4R2 Antibody [NBP2-19914] - Sample (30 ug of whole cell lysate) A: Non-transfected 293T lysates B: PPP4R2 transfected 293T lysate 10% SDS PAGE gel, diluted at 1:5000.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PPP4R2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PPP4R2 Antibody - BSA Free (NBP2-19914) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PPP4R2. The exact sequence is proprietary.
• Localization: Centrosome
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PPP4R2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000-1:10000
• Theoretical MW: 47 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse (80%), Xenopus laevis (80%), Chicken (86%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for PPP4R2 Antibody - BSA Free

• MGC131930
• PP4R2
• protein phosphatase 4, regulatory subunit 2
• serine/threonine-protein phosphatase 4 regulatory subunit 2

Background

Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: PPP4R2