Species: Hu, Mu, Pm
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C atcentrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporallocalization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replicationand required for DNA DSB repair
Bioinformatics
| Entrez |
Human
Mouse
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
151987 |
| Alternate Names |
- MGC131930
- PP4R2
- protein phosphatase 4, regulatory subunit 2
- serine/threonine-protein phosphatase 4 regulatory subunit 2
|
