PPIL5 Antibody - BSA Free

Western Blot: PPIL5 Antibody [NBP2-57485] - Analysis in human testis tissue.

Immunocytochemistry/Immunofluorescence: PPIL5 Antibody [NBP2-57485] - Staining of human cell line PC-3 shows localization to nucleoplasm, nuclear membrane & vesicles.

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PPIL5 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PPIL5 Antibody - BSA Free (NBP2-57485) is a polyclonal antibody validated for use in WB and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: LDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSLEYLDLFGNTFEQPKVLPVIKLQAPLTLLESSART
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LRR1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  PPIL5 Recombinant Protein Antigen (NBP2-57485PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for PPIL5 Antibody - BSA Free

• 4-1BBlrr
• cyclophilin-like 5,4-1BB-mediated-signaling molecule
• leucine rich repeat protein 1
• LRR-1LRR-repeat protein 1
• MGC20689,4-1BBLRR
• peptidylprolyl isomerase (cyclophilin)-like 5,4-1BB-mediated signaling molecule
• Peptidylprolyl isomerase-like 5
• PPIL5

Background

PPIL5 is encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LRR1