Species: Hu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Mouse Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
PPIL5 is encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
122769 |
| Alternate Names |
- 4-1BBlrr
- cyclophilin-like 5,4-1BB-mediated-signaling molecule
- leucine rich repeat protein 1
- LRR-1LRR-repeat protein 1
- MGC20689,4-1BBLRR
- peptidylprolyl isomerase (cyclophilin)-like 5,4-1BB-mediated signaling molecule
- Peptidylprolyl isomerase-like 5
- PPIL5
|
