PPAPDC1B/DPPL1 Antibody - BSA Free

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Western Blot: PPAPDC1B/DPPL1 Antibody [NBP1-76244] - EL4 cell lysate with PPAPDC1B/DPPL1 antibody at (A) 1 and (B) 2 ug/mL.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

PPAPDC1B/DPPL1 Antibody - BSA Free Summary

Description
Novus Biologicals Rabbit PPAPDC1B/DPPL1 Antibody - BSA Free (NBP1-76244) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
Antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human PPAPDC1B. The immunogen is located within amino acids 30 - 80 of PPAPDC1B. Amino Acid Squence: LYRNPYVEAEYFPT
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PLPP5
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Western Blot 1-2 ug/ml
Control Peptide
PPAPDC1B/DPPL1 Peptide (NBP1-76244PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for PPAPDC1B/DPPL1 Antibody - BSA Free

  • diacylglycerol pyrophosphate like 1
  • DPPL1
  • EC 3.1.3.4
  • HTPAPphosphatidate phosphatase PPAPDC1B
  • phosphatidic acid phosphatase type 2 domain containing 1B
  • Phosphatidic acid phosphatase type 2 domain-containing protein 1B

Background

Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide (NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. Knockdown experiments indicated that this protein is involved with multiple cell signaling pathways, including the JAK-Stat3, MAP kinase, and PKC pathways. PPAPDC1B may also potentiate the estrogen receptor pathway by down-regulating DUSP22.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PLPP5
Uniprot