PP14/Glycodelin Antibody [CoraFluor™ 1]

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: CoraFluor 1

PP14/Glycodelin Antibody [CoraFluor™ 1] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human PP14/Glycodelin
  Met19-Phe180 (Glu95Gly)
  Accession # P09466
• Specificity: Detects human PP14/Glycodelin in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: PAEP
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Antigen Affinity-purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for PP14/Glycodelin Antibody [CoraFluor™ 1]

• alpha uterine protein
• GdF
• GdS
• Glycodelin
• glycodelin-A
• glycodelin-F
• glycodelin-S
• MGC138509
• MGC142288
• PAEP
• PEP
• Placental protein 14
• PP14 protein (placental protein 14)
• PP14
• PP14GDPAEGGdA
• pregnancy-associated endometrial a
• Pregnancy-associated endometrial alpha-2 globulin
• pregnancy-associated endometrial alpha-2-globulin
• progestagen-associated endometrial protein (placental protein 14
• progestagen-associated endometrial proteinPEG
• Progesterone-associated endometrial protein

Background

PAEP (Progesterone-associated endometrial protein, glycodelin, PEG, PP14) is a glycoprotein belonging to lipocalin structural superfamily. It shares a sequence homology to beta-lactoglobulins containing a retinol-binding motif and it is mainly produced by secretory and decidualized endometrium in women and by seminal vesicle epithelium in men (1). PAEP function is not clearly understood. However, glycosylated version of PAEP (GdA) has been associated to contraceptive and immunosuppressive activities during reproduction. PAEP is the main protein produced by secretory endometrium during mid-luteal phase of the menstrual cycle and during the first semester of pregnancy. Therefore, PAEP has been linked as an ideal biomarker of endometrial activity and function for in vitro fertilization treated women (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PAEP