PMS1 Antibody (2G10)

Sandwich ELISA: PMS1 Antibody (2G10) [H00005378-M01] - Detection limit for recombinant GST tagged PMS1 is approximately 0.03ng/ml as a capture antibody.

Product Discontinued

PMS1 Antibody (2G10) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: PMS1 (NP_000525, 26 a.a. ~ 135 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KELIENSLDAGATSVDVKLENYGFDKIEVRDNGEGIKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQYVLDGSGHILSQKPS
• Specificity: PMS1 - PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: PMS1
• Purity: Ascites

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Ascites

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PMS1 Antibody (2G10)

• DKFZp781M0253
• FLJ98259
• HNPCC3
• hPMS1
• human homolog of yeast mutL
• mismatch repair gene PMSL1
• PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
• PMS1 protein homolog 1
• PMSL1DNA mismatch repair protein PMS1
• postmeiotic segregation increased (S. cerevisiae) 1
• rhabdomyosarcoma antigen MU-RMS-40.10B
• rhabdomyosarcoma antigen MU-RMS-40.10E

Background

This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PMS1
• Entrez:
  • 5378(Human)
• OMIM:
  • 600258(Human)
• Uniprot:
  • NP_000525(Human)