PLK2 Antibody - BSA Free

Western Blot: PLK2 Antibody [NBP2-15078] - Sample (30 ug of whole cell lysate) A: A549 7. 5% SDS PAGE; antibody diluted at 1:1000.

Immunohistochemistry-Paraffin: PLK2 Antibody [NBP2-15078] - Mouse colon, dilution: 1:500. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

HBI-002 effects on autophagy, lysosomes and cathepsin D.a Immunoblots of autophagy and lysosomal activity markers. b Quantification of autophagy and lysosomal activity markers. Ctsd (p = 0.002, 1-beta = 0.99, N = 8, 4 per group) and Plk2 (p = 0.006, 1-beta = 0.99, N = 8, 4 per group), all other markers p > 0.05. c Representative photomicrographs of sir-lysosome staining in SH-SY5Y human neuroblastomas. d Quantification of sir-lysosome staining p = 0.0002, 1-beta = 0.95, N = 38 cells, air treated n = 23, CO-treated n = 14. Error bars represent the mean +/- SEM. Data are statistically different from each other with *** P < 0.001. Image collected and cropped by CiteAb from the following open publication (//www.nature.com/articles/s41531-024-00763-6), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PLK2 Antibody - BSA Free Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human PLK2. The exact sequence is proprietary.
• Predicted Species: Rat (98%), Bovine (98%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PLK2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 78 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (89%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 20% Glycerol
• Preservative: 0.025% Proclin 300
• Purity: Antigen Affinity-purified

Alternate Names for PLK2 Antibody - BSA Free

• EC 2.7.11
• EC 2.7.11.21
• hPlk2
• hSNK
• PLK2
• PLK-2
• Polo-like kinase 2
• polo-like kinase 2EC 2.7.11.21
• serine/threonine-protein kinase PLK2
• Serine/threonine-protein kinase SNK
• Serum-inducible kinase
• SNK
• SNKpolo-like kinase 2 (Drosophila)

Background

Serum-inducible kinase is a member of the 'polo' family of serine/threonine protein kinases that have a role in normal cell division.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

&#9888; WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for PLK2 Antibody (NBP2-15078)(1)

Publication using NBP2-15078

• Rose KN, Zorlu M, Fassini A et Al. Neuroprotection of low dose carbon monoxide in Parkinson's disease models commensurate with the reduced risk of Parkinson's among smokers NPJ Parkinsons Dis 2024-08-22 [PMID: 39174550]

Bioinformatics

• Gene Symbol: PLK2
• Uniprot:
  • Q9NYY3(Human)