PKHD1 Antibody [DyLight 550]



Product Details

Product Discontinued
View other related PKHD1 Primary Antibodies

Order Details

    • Catalog Number
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

PKHD1 Antibody [DyLight 550] Summary

A synthetic peptide derived from the human PKHD1 protein (within residues 3800-3900). [UniProt# Q8TCZ9]
Membrane; single-pass type I membrane.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 550
DyLight 550 (A=562, E=576)
50mM Sodium Borate
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified


Application Notes
This PKHD1 antibody is useful for peptide ELISA.

Reactivity Notes

Human. Immunogen sequence has 86% identity to mouse.


Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at for more details.

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.


PKHD1 is a type I membrane protein that undergoes regulated proteolysis. Many proteolytic cleavages occur on the ectodomain whereas at least one cleavage occurs on the cytoplasmic portion of PKHD1. The later generates a C-terminal intracellular fragment that localizes to the nucleus. This proteolysis requires activation of protein kinase C (PKC) and release of intracellular calcium. PKHD1 is expressed in the cilia of the bile duct epithelium and leads to abnormalities in the rubric of the ductal plate malformation. The intracellular C-terminus of PKHD1 interacts with calcium modulating cyclophilin ligand (CAML), a protein implicated in calcium signaling. PKHD1 may participate in the mediation of intracellular calcium in the distal nephron in a manner similar to PKD1 and PKD2. Mutations in the PKHD1 gene result in autosomal recessive polycystic kidney disease (ARPKD), a severe form of polycystic kidney disease characterized by enlarged kidneys and congenital hepatic fibrosis.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ELISA, ICC/IF, S-ELISA
Species: Hu
Applications: ICC
Species: Hu, Rt, Ca, Mk, Pm
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, Simple Western, ICC
Species: Hu, Mu
Applications: WB, Simple Western
Species: Hu, Mu
Applications: WB, IP, ICC
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, PEP-ELISA
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Species: Hu, Rt, Po, Bv, Gt
Applications: WB, ELISA, Flow, ICC/IF, IHC-Fr, IHC-P, IP
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, IHC
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Rt, Ca, Mk
Applications: WB, IHC, IHC-P, IP

Publications for PKHD1 Antibody (BC110-60480R) (0)

There are no publications for PKHD1 Antibody (BC110-60480R).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for PKHD1 Antibody (BC110-60480R) (0)

There are no reviews for PKHD1 Antibody (BC110-60480R). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

FAQs for PKHD1 Antibody (BC110-60480R) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional PKHD1 Antibody [DyLight 550] Products

Related Products by Gene

Bioinformatics Tool for PKHD1 Antibody (BC110-60480R)

Discover related pathways, diseases and genes to PKHD1 Antibody (BC110-60480R). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for PKHD1 Antibody (BC110-60480R)

Discover more about diseases related to PKHD1 Antibody (BC110-60480R).

Pathways for PKHD1 Antibody (BC110-60480R)

View related products by pathway.

PTMs for PKHD1 Antibody (BC110-60480R)

Learn more about PTMs related to PKHD1 Antibody (BC110-60480R).

Blogs on PKHD1

There are no specific blogs for PKHD1, but you can read our latest blog posts.

Contact Information

Product PDFs


Gene Symbol PKHD1

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on BC110-60480R below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.