PKHD1 Products

Antibodies
Proteins
PKHD1 Antibody Blocking Pepti ...
PKHD1 Antibody Blocking Peptide
BC110-60479PEP
Species: Hu
Applications: AC
PKHD1 Antibody Blocking Pepti ...
PKHD1 Antibody Blocking Peptide
BC110-60480PEP
Species: Hu
Applications: AC
PKHD1 Recombinant Protein Ant ...
PKHD1 Recombinant Protein Antigen
NBP1-89003PEP
Species: Hu
Applications: AC

Description

Found mainly in the cytoplasm and plasma membrane, PKHD1 plays an important role in protein binding and receptor activity. The protein encoded by PKHD1 has a single transmembrane (TM) spanning domain and various copies of an immunoglobulin-like plexin-transcription-factor domain. More specifically, these transcripts encode products which lack the TM and may be secreted. In humans, PKHD1 is highly expressed in the kidney by acting as a receptor protein in the cortical and medullary collecting ducts. Diseases associated with PKHD1 include polycystic kidney and hepatic disease, liver disease, neoplasia, fibrosis, cancer, adenocarcinoma and prostate cancer.

Bioinformatics

Entrez Human
Uniprot Human
Alternate Names
  • polycystic kidney and hepatic disease 1 (autosomal recessive)