PINCH1/LIMS1 Antibody (591604) [Alexa Fluor® 594]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: 591604
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 594

PINCH1/LIMS1 Antibody (591604) [Alexa Fluor® 594] Summary

• Immunogen: E. coli-derived recombinant human PINCH1
  Ala2-Gly108
  Accession # P48059
• Specificity: Detects human, mouse, and rat PINCH1 in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PINCH1/LIMS1 Antibody (591604) [Alexa Fluor® 594]

• LIM and senescent cell antigen-like domains 1
• LIM and senescent cell antigen-like-containing domain protein 1
• LIMS1
• PINCH1
• PINCH-1
• PINCHPINCH1Particularly interesting new Cys-His protein 1
• Renal carcinoma antigen NY-REN-48

Background

Particularly interesting new Cys-His protein 1 (PINCH1), also known as LIMS1 (LIM and senescent cell antigen-like-containing domain protein 1), is a 37‑40 kDa, widely expressed LIM-only protein. Human PINCH1 is 325 amino acids (aa) in length and contains a tandem array of five LIM domains. Within the region used as an immunogen, human PINCH1 shares 100% and 99% aa sequence identity with mouse and rat PINCH1, respectively. PINCH1 is an effector of integrin and growth factor signaling, coupling surface receptors to downstream signaling molecules involved in the regulation of cell survival, cell proliferation and cell differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.