PINCH1/LIMS1 Antibody (591604) [DyLight 350]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: 591604
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 350

PINCH1/LIMS1 Antibody (591604) [DyLight 350] Summary

• Immunogen: E. coli-derived recombinant human PINCH1
  Ala2-Gly108
  Accession # P48059
• Specificity: Detects human, mouse, and rat PINCH1 in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: LIMS1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PINCH1/LIMS1 Antibody (591604) [DyLight 350]

• LIM and senescent cell antigen-like domains 1
• LIM and senescent cell antigen-like-containing domain protein 1
• LIMS1
• PINCH1
• PINCH-1
• PINCHPINCH1Particularly interesting new Cys-His protein 1
• Renal carcinoma antigen NY-REN-48

Background

The protein encoded by the LIMS1 gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LIMS1