PIK3R4 Antibody (OTI5D1) [FITC]

Product Discontinued

PIK3R4 Antibody (OTI5D1) [FITC] Summary

• Immunogen: Recombinant protein fragment corresponding to amino acids 732-1036 of human PIK3R4 (NP_055417) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PIK3R4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for PIK3R4 Antibody (OTI5D1) [FITC]

• EC 2.7.11.1
• MGC102700
• p150
• phosphatidylinositol 3-kinase-associated p150
• Phosphoinositide 3-kinase adaptor protein
• phosphoinositide 3-kinase regulatory subunit 4
• phosphoinositide-3-kinase, regulatory subunit 4
• phosphoinositide-3-kinase, regulatory subunit 4, p150
• PI3-kinase p150 subunit
• PI3-kinase regulatory subunit 4
• PIK3R4
• VPS 15
• VPS15

Background

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PIK3R4