PI 3-Kinase p110 delta Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

PI 3-Kinase p110 delta Antibody Summary

Immunogen
20 amino acid C-terminal peptide to Phosphoinositide 3 Kinase p110 delta.
Specificity
Binds to a 110 Kd protein. Not likely to cross react with other isoforms due to sequence dissimilarity.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PIK3CD
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
Application Notes
ELISA: Use at a dilution of 1/75000. ICC: Use at a dilution of 1/400. WB: Use at a dilution of 1/3000. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.
Positive Control
Jurkat Lysate (NB800-PC2)

Reactivity Notes

Cross-reacts with Human. Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
KHPO4 and 1 mg/ml BSA, pH 7.4
Preservative
0.01% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PI 3-Kinase p110 delta Antibody

  • EC 2.7.1
  • EC 2.7.1.153
  • p110D
  • P110DELTA
  • Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta
  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • phosphoinositide-3-kinase C
  • phosphoinositide-3-kinase, catalytic, delta polypeptide
  • PI 3Kinase p110 delta
  • PI 3-Kinase p110 delta
  • PI3K
  • PI3K-delta
  • PI3-kinase p110 subunit delta
  • PI3-kinase subunit delta
  • PIK3CD
  • PtdIns-3-kinase subunit delta
  • PtdIns-3-kinase subunit p110-delta

Background

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p110. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K. Four isoforms of p110 has been found; the alpha, beta, gamma, and the delta subunit. The delta isoform is predominantly expressed in leukocytes and has been shown to interact with p85 and GTP-bound Ras via its SH2/SH3 domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for PI 3-Kinase p110 delta Antibody (NB600-1062) (0)

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional PI 3-Kinase p110 delta Products

Bioinformatics Tool for PI 3-Kinase p110 delta Antibody (NB600-1062)

Discover related pathways, diseases and genes to PI 3-Kinase p110 delta Antibody (NB600-1062). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Research Areas for PI 3-Kinase p110 delta Antibody (NB600-1062)

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Blogs on PI 3-Kinase p110 delta.

PI3 Kinase p110 delta - A cell-type specific lipid kinase with essential roles in leukocyte biology
Phosphatidylinositol 3-kinases (PI3Ks) are a group of lipid kinases with important roles in signal transduction. PI3Ks are involved in signal propagation for diverse receptors including tyrosine kinase receptors and G-protein coupled receptors. Cla...  Read full blog post.

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Bioinformatics

Gene Symbol PIK3CD
Entrez