PI 3-Kinase p110 delta Antibody

Product Discontinued

PI 3-Kinase p110 delta Antibody Summary

• Immunogen: 20 amino acid C-terminal peptide to Phosphoinositide 3 Kinase p110 delta.
• Specificity: Binds to a 110 Kd protein. Not likely to cross react with other isoforms due to sequence dissimilarity.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PIK3CD
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000
  • Western Blot 1:100-1:2000
• Application Notes: ELISA: Use at a dilution of 1/75000. ICC: Use at a dilution of 1/400. WB: Use at a dilution of 1/3000. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.
• Control:

  Jurkat Whole Cell Lysate

Reactivity Notes

Cross-reacts with Human. Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: KHPO4 and 1 mg/ml BSA, pH 7.4
• Preservative: 0.01% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PI 3-Kinase p110 delta Antibody

• EC 2.7.1
• EC 2.7.1.153
• p110D
• P110DELTA
• Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta
• phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform
• phosphoinositide-3-kinase C
• phosphoinositide-3-kinase, catalytic, delta polypeptide
• PI 3Kinase p110 delta
• PI 3-Kinase p110 delta
• PI3K
• PI3K-delta
• PI3-kinase p110 subunit delta
• PI3-kinase subunit delta
• PIK3CD
• PtdIns-3-kinase subunit delta
• PtdIns-3-kinase subunit p110-delta

Background

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p110. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K. Four isoforms of p110 has been found; the alpha, beta, gamma, and the delta subunit. The delta isoform is predominantly expressed in leukocytes and has been shown to interact with p85 and GTP-bound Ras via its SH2/SH3 domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PIK3CD
• Entrez:
  • 5293(Human)