Phosphoserine phosphatase Antibody

Western Blot: Phosphoserine phosphatase Antibody [NBP1-28916] - (0.05ug/ml) Analysis of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

Phosphoserine phosphatase Antibody Summary

• Description: Novus Biologicals Goat Phosphoserine phosphatase Antibody (NBP1-28916) is a polyclonal antibody validated for use in WB and ELISA. Anti-Phosphoserine phosphatase Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-RQQVKDNAKWYITD corresponding to C-Terminus according to NP_004568.2.
• Epitope: C-Terminus
• Predicted Species: Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: PSPH
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
  • Western Blot 0.05 - 1 ug/ml
• Application Notes: WB: Approx. 26 kDa band observed in human brain (hippocampus) and in mouse brain lysates (calculated MW of 25.0 kDa band according to human NP_004568.2 and 25.1 kDa band according to mouse NP_598661.1).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Phosphoserine phosphatase Antibody

• L-3-phosphoserine phosphatase
• O-phosphoserine phosphohydrolase
• phosphoserine phosphatase
• PSPase
• PSPEC 3.1.3.3

Background

The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Phosphoserine phosphatase Antibody (NBP1-28916)(1)

Publication using NBP1-28916

• Veeranna, Shetty KT. Phosphoserine phosphatase of human brain: partial purification, characterization,regional distribution, and effect of certain modulators including psychoactivedrugs. Neurochem Res 1990-12-01 [PMID: 1965857]

Bioinformatics

• Gene Symbol: PSPH
• Entrez:
  • 5723(Human)
  • 100678(Mouse)
  • 304429(Rat)
• Uniprot:
  • NP_004568.2(Human)