PHD4/HIF Prolyl Hydroxylase 4 Antibody

ELISA: PHD4/HIF Prolyl Hydroxylase 4 Antibody [46020002]

Product Discontinued

PHD4/HIF Prolyl Hydroxylase 4 Antibody Summary

• Immunogen: This antibody is specific for the N Terminus Region of the target protein.
• Specificity: This product is specific for Human PHD4/HIF Prolyl Hydroxylase 4
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: P4HTM
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:5000-1:20000
• Application Notes: This antibody is useful in ELISA and Western Blot.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for PHD4/HIF Prolyl Hydroxylase 4 Antibody

• EC 1.14.11.-
• EGLN4
• HIFPH4
• HIF-PH4
• HIF-prolyl hydroxylase 4
• HPH-4
• hypoxia-inducible factor prolyl 4-hydroxylase
• Hypoxia-inducible factor prolyl hydroxylase 4
• P4H with transmembrane domain
• P4H-TMFLJ20262
• PH4 hypoxia inducible factor prolyl 4 hydroxylase
• PH-4
• PHD4
• proline 4-hydroxylase
• prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
• Prolyl hydroxlase domain-containing 4
• transmembrane prolyl 4-hydroxylase

Background

The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PHD4/HIF Prolyl Hydroxylase 4 Antibody (46020002)(2)

Publications using 46020002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Bioinformatics

• Gene Symbol: P4HTM
• Uniprot:
  • Q9NXG6(Human)