PGLYRP3/PGRPIA Antibody (187C434) - Azide and BSA Free

Western Blot: PGLYRP3/PGRPIA Antibody (187C434) - Azide Free [NBP2-33249] - Analysis in cell lysates from human brain using this antibody at a dilution of 1:500.

• Reactivity: Hu
• Applications: WB, Flow, ICC/IF
• Clone: 187C434
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

PGLYRP3/PGRPIA Antibody (187C434) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse PGLYRP3/PGRPIA Antibody (187C434) - Azide and BSA Free (NB100-56729) is a monoclonal antibody validated for use in WB, Flow and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against KLH-conjugated synthetic peptide corresponding to amino acids 178-193 of human PGRP-1a.
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse
• Gene: PGLYRP3
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Flow (Cell Surface) reported in scientific literature (Uehara et al (2005))
  • Flow Cytometry 1ul/1 million cells
  • Immunocytochemistry/ Immunofluorescence reported in scientific literature (Uehara et al (2005))
  • Western Blot 1:500-1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: No Preservative
• Purity: Unpurified

Alternate Names for PGLYRP3/PGRPIA Antibody (187C434) - Azide and BSA Free

• peptidoglycan recognition protein 3
• peptidoglycan recognition protein I alpha
• Peptidoglycan recognition protein I-alpha
• Peptidoglycan recognition protein intermediate alpha
• peptidoglycan recognition protein-I-alpha
• PGLYRP3
• PGLYRPIalphaMGC149197
• PGRP1A
• PGRPI alpha
• PGRP-I alpha
• PGRPIA
• PGRP-Ialpha
• PGRPIAPGRP-I-alpha

Background

Primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria (1,2) and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-Ia , and PGRP-I

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PGLYRP3