PGD2 Synthase/PTGDS Antibody [FITC]

Images

 

Product Details

Summary
Product Discontinued
View other related PGD2 Synthase/PTGDS Primary Antibodies

Order Details


    • Catalog Number
      NB110-59911F
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

PGD2 Synthase/PTGDS Antibody [FITC] Summary

Immunogen
The epitope recognized by this antibody maps to region within residue 120-190 of human Prostaglandin D Synthase/Lipocalin. [Swiss-Prot# P41222]
Localization
Endoplasmic reticulum; rough endoplasmic reticulum. Nucleus; nuclear membrane. Golgi apparatus. Cytoplasm; perinuclear region. Secreted protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PTGDS
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10 - 1:500
Application Notes
This Prostaglandin D Synthase/Lipocalin antibody is useful for Western blot analysis where a band can be seen at ~21 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Immunogen has 89% homology to equine, 85% homology to sheep and 82% homology to porcine.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PGD2 Synthase/PTGDS Antibody [FITC]

  • Beta-trace protein
  • Cerebrin-28
  • EC 5.3.99.2
  • Glutathione-independent PGD synthase
  • glutathione-independent PGD synthetase
  • lipocalin-type prostaglandin D synthase
  • Lipocalin-type prostaglandin-D synthase
  • L-PGDS
  • PDS
  • PGD2 Synthase
  • PGD2
  • PGDS2
  • PGDSLPGDS
  • PH2DISO
  • prostaglandin D synthase
  • prostaglandin D2 synthase (21kD, brain)
  • prostaglandin D2 synthase 21kDa (brain)
  • Prostaglandin-D2 synthase
  • prostaglandin-H2 D-isomerase
  • PTGDS

Background

Prostaglandin D Synthase/Lipocalin (L-PGDS) is a brain-derived protein found most abundantly in CSF and it induces neuronal cell protection and neuronal cell loss, depending on the receptor pathway it signals to the target cells. L-PGDS is found secreted as well as localized to RER, nuclear membrane, Golgi apparatus, perinuclear cytoplasm etc and has been detected in arachnoid and menigioma cells, arachnoid trabecular cells, meningeal macrophages and perivascular microglial cells, oligodendrocytes as well as RPE cells. L-PGDS catalyzes the metabolic transformation of PGH2 to PGD2, a prostaglandin implicated in smooth muscle contraction/relaxation and a platelet aggregation inhibitor. It is implicated in several CNS functions including sedation, NREM sleep and PGE2-induced allodynia, and plays anti-apoptotic role in oligodendrocytes. L-PGDS can bind to small non-substrate lipophilic molecules such as biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. L-PGDS has also been suggested to play role in development and maintenance of blood-brain, blood-retina, blood-aqueous humor and blood-testis barriers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-00178
Species: Mu
Applications: WB, IHC, IHC-Fr, IHC-P, PEP-ELISA
NBP1-89522
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-87311
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
NBP1-31589
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-60106
Species: Hu
Applications: WB, IHC, IHC-P
NB100-689
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IHC-P
NBP1-90306
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-59069
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-83013
Species: Hu
Applications: WB, IHC, IHC-P
NBL1-11228
Species: Hu
NBP1-58268
Species: Hu
Applications: WB, IHC, IHC-P
H00008458-M06
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
NBP2-42388
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-34234
Species: Hu
Applications: ICC/IF, IHC-Fr, IHC-P
NBP2-19014
Species: Hu
Applications: WB, IHC, IHC-P

Publications for PGD2 Synthase/PTGDS Antibody (NB110-59911F) (0)

There are no publications for PGD2 Synthase/PTGDS Antibody (NB110-59911F).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for PGD2 Synthase/PTGDS Antibody (NB110-59911F) (0)

There are no reviews for PGD2 Synthase/PTGDS Antibody (NB110-59911F). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

FAQs for PGD2 Synthase/PTGDS Antibody (NB110-59911F) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional PGD2 Synthase/PTGDS Products

Bioinformatics Tool for PGD2 Synthase/PTGDS Antibody (NB110-59911F)

Discover related pathways, diseases and genes to PGD2 Synthase/PTGDS Antibody (NB110-59911F). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for PGD2 Synthase/PTGDS Antibody (NB110-59911F)

Discover more about diseases related to PGD2 Synthase/PTGDS Antibody (NB110-59911F).
 

Pathways for PGD2 Synthase/PTGDS Antibody (NB110-59911F)

View related products by pathway.

Research Areas for PGD2 Synthase/PTGDS Antibody (NB110-59911F)

Find related products by research area.

Blogs on PGD2 Synthase/PTGDS

There are no specific blogs for PGD2 Synthase/PTGDS, but you can read our latest blog posts.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our PGD2 Synthase/PTGDS Antibody [FITC] and receive a gift card or discount.

Bioinformatics

Gene Symbol PTGDS
Entrez