PEX14 Antibody - BSA Free

Immunoprecipitation: PEX14 Antibody [NBP1-71841] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-PEX14 antibody used for IP at 6 mcg/mg lysate. PEX14 was also immunoprecipitated by rabbit anti-PEX14 antibody NBP1-71842 which recognizes a downstream epitope.

• Reactivity: Hu
• Applications: IP, WB (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

PEX14 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PEX14 Antibody - BSA Free (NBP1-71841) is a polyclonal antibody validated for use in ICC/IF and IP. Anti-PEX14 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen for this product maps to a region between residue 250 and 300 of human Peroxisomal Biogenesis Factor 14 using the numbering given in entry NP_004556.1 (GeneID 5195).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PEX14
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2-5 ug/mg lysate
• Application Notes: Western Blot Not recommended

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PEX14 Antibody - BSA Free

• dJ734G22.2
• MGC12767
• NAPP2
• NF-E2 associated polypeptide 2
• peroxin-14
• peroxisomal biogenesis factor 14
• Peroxisomal membrane anchor protein PEX14
• peroxisomal membrane anchor protein Pex14p
• peroxisomal membrane protein PEX14
• Pex14p
• PTS1 receptor docking protein
• PTS1 receptor-docking protein

Background

This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PEX14 Antibody (NBP1-71841)(2)

Publications using NBP1-71841

• Wong, CP, CP Effect of Peroxisome Proliferation on Replication of Emerging RNA Viruses Thesis 2022-01-01 (ICC/IF, Monkey, Human)
• Knoblach B, Ishida R, Hobman TC, Rachubinski RA Peroxisomes exhibit compromised structure and matrix protein content in SARS-CoV-2-infected cells Molecular biology of the cell 2021-05-19 [PMID: 34010015]

Bioinformatics

• Gene Symbol: PEX14
• Uniprot:
  • NP_004556.1(Human)