Recombinant Mouse Peroxiredoxin 2 His Protein

SDS-Page: Recombinant Mouse Peroxiredoxin 2 Protein [NBP2-61185] - 15 % SDS-PAGE (3ug)

• Reactivity: Mu
• Applications: PAGE, Enzyme Activity
• Concentration: 1 mg/ml

Recombinant Mouse Peroxiredoxin 2 His Protein Summary

• Description: A bioactive recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-198 of Mouse Peroxiredoxin 2alpha
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMASGNA QIGKSAPDFT ATAVVDGAFK EIKLSDYRGK YVVLFFYPLD FTFVCPTEII AFSDHAEDFR KLGCEVLGVS VDSQFTHLAW INTPRKEGGL GPLNIPLLAD VTKSLSQNYG VLKNDEGIAY RGLFIIDAKG VLRQITVNDL PVGRSVDEAL RLVQAFQYTD EHGEVCPAGW KPGSDTIKPN VDDSKEYFSK HN

• Details of Functionality: Specific activity is > 3,000 pmol/min/ug, Activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for minute.
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: PRDX2
• Purity: >90%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • Enzyme Activity
  • SDS-Page
• Theoretical MW: 24.3 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol, 1 mM DTT
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Mouse Peroxiredoxin 2 His Protein

• EC 1.11.1
• MGC4104
• Natural killer cell-enhancing factor B
• natural killer-enhancing factor B
• NKEF-B
• NKEFBNKEF-B
• Peroxiredoxin 2
• peroxiredoxin-2
• PRDX2
• PRPTDPX1
• PRX2
• PRXII
• TDPX1
• thiol-specific antioxidant 1
• Thiol-specific antioxidant protein
• Thioredoxin peroxidase 1
• Thioredoxin-dependent peroxide reductase 1
• torin
• TPX1
• TSA
• TSAEC 1.11.1.15

Background

Peroxiredoxin 2 encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for Peroxiredoxin 2 Recombinant Protein (NBP2-61185)(1)

Publication using NBP2-61185

• Yang Du, Jinjin Wang, Jia Zhang, Ning Li, Guangshuo Li, Xinmin Liu, Yijun Lin, Dandan Wang, Kaijiang Kang, Liheng Bian, Xingquan Zhao Intracerebral hemorrhage‐induced brain injury in mice: The role of peroxiredoxin 2‐Toll ‐like receptor 4 inflammatory axis CNS Neuroscience & Therapeutics 2024-03-22 [PMID: 38516845]

Bioinformatics

• Gene Symbol: PRDX2