Recombinant Human Peroxiredoxin 2 Protein

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SDS-Page: Recombinant Human Peroxiredoxin 2 Protein [NBC1-25855]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Func, PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human Peroxiredoxin 2 Protein Summary

Description
An un-tagged recombinant protein corresponding to the amino acids 1-198 of Human Peroxiredoxin 2

Source: E.coli

Amino Acid Sequence: MASGNARIGK PAPDFKATAV VDGAFKEVKL SDYKGKYVVL FFYPLDFTFV CPTEIIAFSN RAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTRR LSEDYGVLKT DEGIAYRGLF IIDGKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQYTDEHGE VCPAGWKPGS DTIKPNVDDS KEYFSKHN

Details of Functionality
Specific activity is >2,000 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for minute.
Source
E. coli
Protein/Peptide Type
Biologically Active Protein
Gene
PRDX2
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
21.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human Peroxiredoxin 2 Protein

  • EC 1.11.1
  • MGC4104
  • Natural killer cell-enhancing factor B
  • natural killer-enhancing factor B
  • NKEF-B
  • NKEFBNKEF-B
  • Peroxiredoxin 2
  • peroxiredoxin-2
  • PRDX2
  • PRPTDPX1
  • PRX2
  • PRXII
  • TDPX1
  • thiol-specific antioxidant 1
  • Thiol-specific antioxidant protein
  • Thioredoxin peroxidase 1
  • Thioredoxin-dependent peroxide reductase 1
  • torin
  • TPX1
  • TSA
  • TSAEC 1.11.1.15

Background

Peroxiredoxin 2, also known as PRDX2, is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Peroxiredoxin 2 may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. If Peroxiredoxin 2 protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer. Recombinant human Peroxiredoxin 2 protein was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

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Bioinformatics

Gene Symbol PRDX2
Entrez