Peptidylglycine alpha-Amidating Monooxygenase/PAM Antibody [mFluor Violet 610 SE]

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: mFluor Violet 610 SE

Peptidylglycine alpha-Amidating Monooxygenase/PAM Antibody [mFluor Violet 610 SE] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human PAM
  Phe21-Val817
  Accession # P19021
• Specificity: Detects human PAM in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: PAM
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Peptidylglycine alpha-Amidating Monooxygenase/PAM Antibody [mFluor Violet 610 SE]

• PAL
• PAM
• pancreatic peptidylglycine alpha-amidating monooxygenase
• peptidyl alpha-amidating enzyme
• peptidyl-alpha-hydroxyglycine alpha-amidating lyase
• peptidylamidoglycolate lyase
• peptidylglycine 2-hydroxylase
• peptidyl-glycine alpha-amidating monooxygenase
• peptidylglycine alpha-amidating monooxygenase
• peptidylglycine alpha-hydroxylating monooxygenase
• PHM

Background

PAM encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PAM